APOE4 triples Alzheimer's risk. New study finds the culprit: fat in brain cells
MIT team traces APOE4's damage to lipid droplets, opening a new drug target beyond amyloid and tau.

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MIT team traces APOE4's damage to lipid droplets, opening a new drug target beyond amyloid and tau.
The Claude maker's 5% share pledge, worth $48bn, is a bid to win over regulators and investors before its stock market listing.
Tech leaders want the shares given directly to Americans, not parked in a foundation.
The AI company is locking a slice of its value to social causes before a potential November IPO, with roughly 20% of shares now pledged to the public good.
GlobalFoundries CEO Tim Breen says the whole industry is in short supply, and Japan's up-to-$21B commitment to two Malta, New York plants shows sovereign capital is now funding US chip capacity.
Trump's term limit is gutting the MAGA merch economy - sellers are slashing prices, closing shops, and pivoting to rallies before 2027.
New iPhone Duo preorders won't ship until January 25, 2027, while early buyers get theirs in October. Tim Cook sees supply constraints tightening.
Two law enforcement officials say the toll is preliminary and could change; Bend police confirm the suspect is dead.
Former Disney TV chief Peter Rice takes over Netflix's $20 billion content budget on October 26, replacing Bela Bajaria as viewership growth stalls.
Activision's top marketer says Rockstar's blockbuster will drive players back to consoles and into Modern Warfare 4, even as the company admits its recent strategy failed.
Shook Research rebranded to Veritant after its founder admitted paying Forbes' editor for favorable coverage. Here is what that means for every media-adjacent business.
The actor who made Walter White Jr. a household name pushed Hollywood on inclusion long after the credits rolled.